Introduction
Promise, Peril and Progress
by Jesse Emspak
Section 1: What is Gene Therapy?
1.1 The Gene Fix
by Esther Landhuis
1.2 Gene Therapy Is Coming of Age
by Lauren Gravitz
Section 2: The Promise
2.1 Four Success Stories in Gene Therapy
by Jim Daley
2.2 Fixing Wasting Muscles
by Dina Fine Maron
2.3 Out of the Silence
by Dina Fine Maron
2.4 How Gene Therapy Can Reverse a Form of Congenital Blindness
by Jean Bennett and Katherine A. High
2.5 Messenger RNA Therapies Finally Arrived
by Drew Weissman
Section 3: The Challenges
3.1 Overcoming Gene Therapy’s Long Shadow
by Tanya Lewis
3.2 The Challenge of Finding Genome-Based Cancer Treatments
by Jonathan R. Goodman
3.3 What Gene Therapy Needs Now: A Good Off Switch
by Jim Kozubek
Section 4: The Human Factor: History, Ethics and Assumptions
4.1 High Hopes: Balancing Promise and Reality
by Marla Broadfoot
4.2 We Need More Diversity in Genomic Databases
by Jonas Korlach
4.3 The Human Genome and the Making of a Skeptical Biologist
by C. Brandon Ogbunu
4.4 The Inflated Promise of Genomic Medicine
by Erik Parens
4.5 All of Us
by Stephanie Devaney
