Squalane vs. Hyaluronic Acid: Derms Explain the Difference

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Squalane is an emollient, which means that it works to soften skin. It comes from squalene, a natural component of sebum produced by the skin that is too unstable to formulate into skincare. Squalane, on the other hand, works well when whipped into skincare products. “Squalane, which is created when squalene is hydrogenated, has many benefits for the skin, including emollition, antioxidant, and anticarcinogenic properties,” says Marcus. “Squalane is nonirritating and can calm down redness and inflammation, making it an excellent choice for those with sensitive skin or inflammatory skin conditions.”

Though squalane is primarily used as an emollient, it has other benefits when it’s used in skincare products. ​​”Squalane is super hydrating and is used primarily as a moisturizer but also has antioxidant and skin barrier–boosting properties,” says Marcus. “It can also help to regulate skin’s oil production.”



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